Micky van de Ven Brace Ends The Toffees' Unbeaten Streak at New Home Ground
Micky van de Ven emerged as the initial defender to score twice in a English top-flight match for Spurs since Jan Vertonghen in spring 2013.
At a glance
The Spurs defender nods home two times in opening period
Everton's defender has goal ruled after video check
Pape Matar Sarr nets third in dying moments
The defeat is the Merseyside club's first at their new ground
The Tottenham defender scored twice as Tottenham extended their unbeaten run in away games in the top division and handed the Toffees their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their five previous fixtures at their recently opened stadium at the dockside location, having departed their historic home behind after 133 years at the end of the previous campaign.
But Tottenham's leader Van de Ven pounced on two occasions from set-pieces in the opening 45 minutes to place their impressive record at risk, and they were unable to mount a comeback before the midfielder - set up by former Toffees attacker Richarlison - headed home a third to put the game to bed.
Jake O'Brien believed he had levelled the tally a short while after Van de Ven's opener, directing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, failed to convert a number of chances, while Vicario made a series of fine saves to guarantee Tottenham went five away games without defeat in the Premier League.
But the video assistant referee intervened, instructing the match official to check the goal on the pitchside monitor and the referee ruled that Jack Grealish and the attacker were in an illegal position and had impeded with the Spurs keeper.
The win moves the manager's team up to third in the Premier League, five points off local foes and leaders Arsenal.
The Merseyside club stay 14th and are half a dozen points clear of the relegation zone.
Spurs breakdown: Van de Ven fulfils duties at both ends of pitch
Following a drab weekday display in the Champions League against Monaco, where they managed a mere attempts on goal, the manager chose the French striker up front instead of ex-Everton forward Richarlison.
The new arrival was unable to influence the game before being substituted for the substitute after an hour on the field, but it emerged he proved unnecessary in the final outcome.
Centre-back the Dutchman converted into an offensive threat to be reckoned with.
Spurs' first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball back across the face of goal for an free the defender to score.
And Ven de Ven - filling in as skipper in the Argentine's unavailability - notched his second in first-half stoppage time as he outjumped Jordan Pickford to nod in.
Van de Ven was just as outstanding in defensive duties, partnering well with Kevin Danso as the duo dealt superbly with the 34 crosses thrown their way by Everton.
Everton analysis: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it seems the freshness may have faded somewhat and fans flocked to the gates after the midfielder's third for Spurs.
The break in Everton's unbeaten home run will not be a massive worry for the manager, but their striker situation are.
Beto and the other striker - the Everton's pair of established centre-forwards - had netted only one league goal between them before Sunday's outing.
And they were unable to contribute to that miserable record on a damp and dreary evening on Merseyside.
The striker's performance was epitomized when he chose to overhead kick a clear chance from near the goal, even with having room and time to reposition for a simpler attempt that would have tested the keeper.
Barry, as well, failed to influence the game after coming on for the starter in the 65th minute.
It wasn't for a lack of opportunity. Most of the home side's attacks came through the winger and Ndiaye, who relentlessly delivered dangerous balls into the Spurs box.
What next for these two sides?
Everton: Moyes' men head to Sunderland in the top flight on Monday, 3 November at 20:00 GMT.
Tottenham: Spurs travel to Newcastle's ground on late October for their fourth-round Carabao Cup tie against the Magpies.